What is meant by bone marrow infiltration?
Comment: Histiocytic infiltration is defined as an increase in the numbers of macrophages or. histiocytes in the bone marrow. These macrophages may be vacuolated and/or contain variable. amounts of cellular debris, cholesterol clefts, or pigment (e.g., hemosiderin) and are usually.
What is infiltration in hydrologic cycle?
INFILTRATION. Infiltration is the physical process involving movement of water through the boundary area where the atmosphere interfaces with the soil. The surface phenomenon is governed by soil surface conditions. Water transfer is related to the porosity of the soil and the permeability of the soil profile.
What is infiltration rate in hydrology?
The infiltration rate is the velocity or speed at which water enters into the soil. It is usually measured by the depth (in mm) of the water layer that can enter the soil in one hour. An infiltration rate of 15 mm/hour means that a water layer of 15 mm on the soil surface, will take one hour to infiltrate.
How does infiltration occur in the water cycle?
Infiltration is the process by which precipitation or water soaks into subsurface soils and moves into rocks through cracks and pore spaces. Infiltration occurs in the upper layers of the ground but may also continue further downwards into the water table. …
What causes bone marrow infiltration?
Malignancy causing bone marrow infiltration – eg, lymphoma, multiple myeloma, carcinoma, hairy cell leukaemia. Myelodysplasia. Ionising radiation (including therapeutic radiotherapy). Viruses (hepatitis B virus, Epstein-Barr virus, parvovirus B19).
How do humans affect infiltration?
Agriculture has been the cause of significant modification of landscapes throughout the world. Tillage of land changes the infiltration and runoff characteristics of the land surface, which affects recharge to ground water, delivery of water and sediment to surface-water bodies, and evapotranspiration.
What are the factors that affect infiltration?
Factors that affect infiltration
- Precipitation. Precipitation can impact infiltration in many ways.
- Soil characteristics. The porosity of soils is critical in determine the infiltration capacity.
- Soil moisture content.
- Organic materials in soils.
- Land cover.
- General hydrologic budget.
- Richards’ equation (1931)
Why is my bone marrow not producing white blood cells?
A low white blood cell count usually is caused by: Viral infections that temporarily disrupt the work of bone marrow. Certain disorders present at birth (congenital) that involve diminished bone marrow function. Cancer or other diseases that damage bone marrow.
Why does histiocyte infiltration occur in the bone marrow?
Histiocytic infiltration usually represents a reactive process, the reasons for which are not well defined in rodents. Compounds that are cytotoxic and cause necrosis of the bone marrow may result in increased numbers of macrophages, which serve to remove the cellular debris.
Where is diffuse bone marrow infiltration in acute leukemia?
Diffuse bone marrow infiltration is shown with a variegated pattern in the pelvic bones, the lumbar spine and bilateral proximal femur. In acute leukemiasa diffuse MR pattern is typical but not very specific.
Is the blood count Normal with bone marrow infiltration?
In malignant infiltration of bone marrow, the blood count may be normal although pancytopenia may occur and there may be leukoerythroblastic blood picture. Malignant infiltration of bone marrow by the metastatic tumor may be focal or diffuse.
Can a bone marrow infiltration cause hematopoiesis?
In addition, any condition capable of causing bone marrow injury or inflammation can result in increased macrophages. In other species (humans and dogs), noninflammatory histiocytic infiltrates have been associated with bone marrow hyperplasia, ineffective hematopoiesis, or increased breakdown of blood cells.