What is the meaning of phagolysosome?
: a digestive vesicle formed within a cell by the fusion of a phagosome containing ingested material and a lysosome containing hydrolytic enzymes.
What does a phagocyte mean?
A type of immune cell that can surround and kill microorganisms, ingest foreign material, and remove dead cells. It can also boost immune responses. Monocytes, macrophages, and neutrophils are phagocytes. A phagocyte is a type of white blood cell.
What is phagosome in biology?
In cell biology, a phagosome is a vesicle formed around a particle engulfed by a phagocyte via phagocytosis. Phagosomes have membrane-bound proteins to recruit and fuse with lysosomes to form mature phagolysosomes.
What happens to residual bodies?
In lysosomal digestion, residual bodies are vesicles containing indigestible materials. Residual bodies are either secreted by the cell via exocytosis (this generally only occurs in macrophages), or they become lipofuscin granules that remain in the cytosol indefinitely.
What are Pinosomes?
Pinosome: A tiny fluid-filled vesicle (bubble) within a cell. Pinosomes are created in the process of pinocytosis in which tiny incuppings called caveolae (little caves) in the surface of the cell close and then pinch off to form pinosomes within the cytoplasm of the cell.
What are primary lysosomes?
Primary lysosomes (arrow, micrograph 1) are homogeneous, dense, membrane-bound organelles packed with acid hydrolases capable of breaking down polymers of all types. A major function of lysosomes is to breakdown or digest material entering from the extracellular environment.
What are the stages of phagocytosis?
The process of phagocytosis involves several phases: (i) detection of the particle to be ingested, (ii) activation of the internalization process, (iii) formation of a specialized vacuole called phagosome, and (iv) phagosome maturation.
How do phagocytes fight infection?
Phagocytes surround any pathogens in the blood and engulf them. They are attracted to pathogens and bind to them. The phagocytes membrane surrounds the pathogen and enzymes found inside the cell break down the pathogen in order to destroy it.
What does Histogenesis mean?
: the formation and differentiation of tissues.
What are the Autophagosomes?
Autophagosomes are double-membrane sequestering vesicles that are the hallmark of the intracellular catabolic process called macroautophagy. They are formed by the orchestrated interplay of the AuTophaGy-related (ATG) proteins.
Which is the best definition of the phagolysosome?
phag·o·ly·so·some. A body formed by union of a phagosome or ingested particle with a lysosome having hydrolytic enzymes. phagolysosome. a cytoplasmic body formed by the fusion of a phagosome, or ingested particle, with a lysosome containing hydrolytic enzymes. The enzymes digest most of the material within the phagosome.
What happens when lysosome and phagosome collide?
It takes place when the phagosome’s and lysosome’s membranes ‘collide’, at which point the lysosomal contents—including hydrolytic enzymes —are discharged into the phagosome in an explosive manner and digest the particles that the phagosome had ingested.
How is a cytoplasmic body formed in a phagosome?
a cytoplasmic body formed by the fusion of a phagosome, or ingested particle, with a lysosome containing hydrolytic enzymes. The enzymes digest most of the material within the phagosome. phag·o·ly·so·some. A body formed by union of a phagosome or ingested particle with a lysosome having hydrolytic enzymes.
What is the role of TlyA in the phagolysosome?
The presence of specific protein domains of TlyA in slow growing mycobacterial pathogen indicates its role in facilitating the internalization of mycobacteria inside the host cells by modulation of the phagolysosome maturation pathway immediately after entry into macrophages.