Is seminoma cancer aggressive?
Testicular cancer is a rare malignancy, with only about 8,000 cases diagnosed in the United States each year. When the disease does strike, however, it can be highly aggressive. About two-thirds of patients are first diagnosed with disease that has spread, or metastasized.
Is seminoma cancer curable?
Testicular cancer is very curable. While a cancer diagnosis is always serious, the good news about testicular cancer is that it is treated successfully in 95% of cases. If treated early, the cure rate rises to 98%.
Is seminoma a cancer?
A type of cancer that begins in germ cells in males. Germ cells are cells that form sperm in males or eggs in females. Seminomas occur most often in the testicle, but they may also occur in other areas of the body, such as the brain, chest, or abdomen.
What is non seminoma cancer?
(NON-seh-mih-NOH-muh) A type of cancer that begins in cells that form sperm or eggs. There are several types of nonseminoma tumors, including embryonal carcinoma, malignant teratoma, choriocarcinoma, and yolk sac tumor. These tumors are usually made up of more than one type of cancer cell.
Is non seminoma malignant?
Testicular non-seminomatous giant cell tumor (NSGCT) is curable cancer. It can be managed ideally if the medical health providers know the knowledge of its pathophysiology and route of spread. It is a malignant but curable tumor if diagnosed and managed properly.
How does seminoma spread?
Seminoma spreads most commonly by the lymphatic route alone. The lymphatics that accompany the testicular vessels exit from the testis through the inguinal ring to the retroperitoneal para-aortic lymph nodes and typical patterns of spread occur according to the side of the primary tumour are well recognised .
What is the etiology of testicular seminoma?
Etiology. Etiology is unknown but tumors are thought to arise from an embryonic germ cell leading to testicular intraepithelial neoplasia (the precursor to classical seminoma). Cryptorchidism is a risk factor for the development of testicular seminomatous germ cell tumors.
When to know if you have seminoma scrotum?
Clinical description. Seminoma usually presents in males between the ages of 30-40. A painless mass in the scrotum is indicative of disease. A long-standing hydrocele may be noted causing a feeling of heaviness in the testicle.
What kind of blood test is needed for seminoma?
Measurement of tumor markers in blood such as alpha-fetoprotein (AFP), beta human chorionic gonadotropin (BHC) and lactate dehydrogenase (LDH) is needed as it can be useful in cases where the tumor is still very small. Classical seminoma does not secrete AFP and patients with raised levels of this tumor marker are given a diagnosis of non-seminoma.
Can a non seminoma testicle be removed without AFP?
Classical seminoma does not secrete AFP and patients with raised levels of this tumor marker are given a diagnosis of non-seminoma. After surgical removal of testicle, histopathological characteristics are analyzed and a stage can be assigned.