What is TSP illness?

For several decades the term “tropical spastic paraparesis” (TSP) has been used to describe a chronic and progressive disease of the nervous system that affects adults living in equatorial areas of the world and causes progressive weakness, stiff muscles, muscle spasms, sensory disturbance, and sphincter dysfunction.

How is ham TSP diagnosed?

As definitive laboratory diagnosis of HAM/TSP is based on the presence of anti-HTLV-1 antibodies in the blood and CSF. Robust humoral immune responses against HTLV-1 antigens have been reported in peripheral blood and CSF of HAM/TSP patients.

What is TSP test?

Diagnostic method. Lumbar puncture, MRI. Treatment. Interferon alpha, corticosteroids. Tropical spastic paraparesis (TSP), is a medical condition that causes weakness, muscle spasms, and sensory disturbance by human T-lymphotropic virus resulting in paraparesis, weakness of the legs.

What does tsp mean in medicine?

Tropical Spastic Paraparesis. About TSP medical condition | Patient. Neurology.

What is the treatment of ham?

While there is no cure for HAM/TSP or US Food and Drug Administration (FDA) approved treatments, there are many strategies available to manage the symptoms. Spasticity (muscle stiffness) may be treated with medications, including baclofen or tizanidine.

What are the symptoms of ham?

Signs and symptoms of HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) vary but may include:

Slowly progressive weakness and spasticity of one or both legs.
Exaggerated reflexes (hyperreflexia)
Stiff muscles.
Muscle contractions in the ankle (ankle clonus)
Lower back pain.

What does TSP mean in nursing?

What does TSP stand for in nutrition?

Triple superphosphate (TSP) was one of the first high-analysis phosphorus (P) fertilizers that became widely used in the 20th century. Technically, it is known as calcium dihydrogen phosphate and as monocalcium phosphate, [Ca(H₂PO₄)₂ . H₂O].

Can HTLV go away?

Most people infected with HTLV-I or HTLV–II will have few to no symptoms but can pass the infection on to others. After the initial infection, the virus never completely goes away but remains in the body in an inactive (latent) form.

Is there a link between HTLV-2 and HAM / TSP?

There is evidence that HTLV-II infection is associated with a disease similar or identical to HAM/TSP. Furthermore, a spinocerebellar syndrome and an increased susceptibility to infections (pneumonia, tuberculosis, and bladder infections) have also been associated.

How long is the latency period for HAM / TSP?

The latency between infection and development of symptoms is longer than 20 years in most ATL cases. HAM/TSP usually develops in the fourth or fifth decades but onset at extremes of age is observed. The latency period of HAM/TSP is shorter than in ATL, and women are more affected.

What kind of drugs are used for HAM / TSP?

Several drugs have been used in the treatment of HAM/TSP including Interferon, danazol, high dose vitamin C, azatioprine, antivirals employed in treatment of HIV infection (zidovudine and lamivudine), valproic acid among others, but results were disappointing. High dose steroids might provide transient improvement in early stages of disease.