What does angiotensin II receptor antagonist do?
Angiotensin II receptor blockers help relax your veins and arteries to lower your blood pressure and make it easier for your heart to pump blood. Angiotensin is a chemical in your body that narrows your blood vessels. This narrowing can increase your blood pressure and force your heart to work harder.
What are sartan drugs?
Valsartan, losartan, irbesartan and other “-sartan” drugs are a class of medicines known as angiotensin II receptor blocker (ARBs) used to treat high blood pressure and heart failure.
What does an angiotensin receptor blocker do?
ARBs work by blocking receptors that the hormone acts on, specifically AT1 receptors, which are found in the heart, blood vessels and kidneys. Blocking the action of angiotensin II helps to lower blood pressure and prevent damage to the heart and kidneys.
Which sartan drug is best?
Based on the results of robust, well-designed trials, losartan and irbesartan have been indicated for the treatment of diabetic nephropathy and should be the ARBs of choice in these patients. Valsartan and candesartan have also shown some benefits in this population.
Do ARBs affect kidneys?
Blood pressure reduction by systemic vasodilation with an ARB contributes to its beneficial effects in treating kidney disease. Furthermore, ARB-induced renal vasodilation results in an increase in renal blood flow, leading to improvement of renal ischemia and hypoxia.
Which Arb has the least side effects?
Is Atacand an angiotensin receptor blocker (ARB)?
Angiotensin Receptor Blockers (ARBs) are used in patients with high blood pressure and other conditions. Brand names include Atacand, Avapro, Benicar, Cozaar, Diovan, Micardis, and Teveten. ARBs are also sold in combination with other medications.
What does angiotensin 2 do?
Angiotensin 2 is a potent vasopressor, acting on vascular endothelial receptors. The two types of angiotensin 2 receptors present in the heart and vasculature smooth muscle that are responsible for signal transduction in mediating the vasoconstrictive action of angiotensin 2 are the angiotensin 1…
What is an ARB medication?
Angiotensin receptor blockers ( ARBs for short) are medicines that are often used to treat high blood pressure. These medicines have names that end in “sartan”.