Is adenocarcinoma of the cervix aggressive?
Small cell cancers are sometimes found alongside other more common types of cervical cancers, such as squamous cell carcinoma and adenocarcinoma. Small cell cancers tend to grow very fast and are the most aggressive type of cervical cancer.
What is a Mesonephric adenocarcinoma?
Mesonephric adenocarcinoma (MNAC) is a rare tumor of the female genital tract, which originates from mesonephric duct remnants. Its diagnosis is pathologically challenging, because MNAC may exhibit a mixture of morphological patterns that complicates the differential diagnosis.
Is an adenocarcinoma malignant?
The malignant tumors are adenocarcinomas, which overtake healthy tissue inside an organ and may spread to other parts of the body. Adenocarcinomas are generally first seen as a thickened, plaque-like white mucous membrane, according to the National Cancer Institute.
How fast does cervical adenocarcinoma spread?
Cervical cancer is a slow-growing malignancy. In fact, once cells in the cervix begin to undergo abnormal changes, it can take several years for the cells to grow into invasive cervical cancer.
What is Mesonephric kidney?
The mesonephric kidney is an embryonic organ that disappears in all mammalian species when the permanent kidney—the metanephros—is functional. The epididymal ducts and the rete ovarii are derived from the mesonephros in adult males and females, respectively.
What is Paramesonephric duct?
The müllerian ducts are the progenitors of the upper female genital tract and develop into the fallopian tubes at their cranial ends and fuse to form the uterus and upper part of the vagina at their caudal ends.
Should I get a hysterectomy if I have precancerous cells?
If the precancerous disease is more extensive or involves adenocarcinoma in situ (AIS), and the woman has completed childbearing, a total hysterectomy may be recommended. 1 During a total hysterectomy, the entire uterus (including the cervix) is removed.
What kind of pathology does mesonephric adenocarcinoma show?
Comment: This tumor demonstrates several distinct histologic patterns (tubules, glandular and papillary regions) with associated peripheral mesonephric remnants. By immunohistochemistry, this tumor shows diffuse and strong expression of GATA3 and PAX8 and no expression of ER.
How is mesonephric carcinoma of the cervix treated?
The treatment may involve a combination of surgery, chemotherapy, and radiation therapy. The prognosis of Mesonephric Carcinoma of Uterine Cervix depends upon a set of several factors including the stage of the tumor, age of the individual, the size of the tumor, and many other factors.
Are there any endometrial mesonephric like carcinomas?
Endometrial mesonephric-like carcinomas (MLCa) are uncommon with <50 reported cases thus far. Previous studies have characterized the histologic, immunohistochemical, and molecular features of MLCa; however, there is limited information with respect to outcome.
Is the MLCA a low grade endometrioid carcinoma?
The behavior of MLCa was compared with low-grade endometrioid carcinomas (ECas) and uterine serous carcinomas (USCs) treated at our institution from 2004 to present.