Can Purpura affect pregnancy?
Findings of our study reveal that, pregnancy in women with idiopathic thrombocytopenic purpura can be safe. Several other researchers have reported similar results in previous studies, (2-5).
Can I get pregnant with ITP?
ITP in Pregnancy. A diagnosis of the autoimmune disease ITP may change many things about your life, but fortunately it doesn’t prevent you from becoming pregnant—or having a perfectly healthy baby.
How common is ITP in pregnancy?
Immune thrombocytopenia (ITP)  occurs in one or two of every 1,000 pregnancies , and accounts for 5% of cases of pregnancy-associated thrombocytopenia.
Can pregnancy cause petechiae?
Pregnant women with immune thrombocytopenia (ITP) can be asymptomatic or can present with a history of easy bruisability, bleeding into the mucous membranes (epistaxis or gingival bleeding), or petechiae. They may have a history of menorrhagia or menometrorrhagia prior to pregnancy.
Can low platelets harm my baby?
Risks for mom and baby Low platelet counts can lead to: Inability to have an epidural during labor due to a risk of epidural hematoma, in which abnormal blood collection in the spine can cause spinal cord damage. Increased bleeding at the time of vaginal or cesarean section delivery.
Can you get pregnant with low platelets?
A low platelet count does not prevent a woman from becoming pregnant or delivering a fine, healthy baby. However, the situation does require special attention and close coordination between the woman’s hematologist, obstetrician, and pediatrician.
How do you know if you are anemic during pregnancy?
Anemia signs and symptoms include:
- Pale or yellowish skin.
- Irregular heartbeats.
- Shortness of breath.
- Dizziness or lightheadedness.
- Chest pain.
- Cold hands and feet.
How is the ITPA gene related to anemia?
ITPA gene is associated with protection of anemia in patients with chronic hepatitis during antiviral therapy. We concluded that ITPase activity plays an important function and that ATP concentration changes due to therapy are related to the Hb decreasing mechanism in the early period of therapy with HCV treatment
How are ITPA polymorphisms related to hepatitis C?
All ITPA polymorphisms considered were shown to be significantly associated with anemia onset in chronic hepatitis C treated patients. ITPA protects against ribavirin-induced anemia, but is not associated with sustained virological response rate. ITPA variants are associated with reduced risk of hepatitis C relapse.
How is the ITPA gene related to Aza / 6-MP?
It is suggested that the ITPA gene mutation is closely related to adverse reactions of AZA/6-MP in Japanese patients, and screening for the mutant allele is useful for predicting the most serious adverse reactions
How does ITPA deficiency affect the virologic response?
ITPA deficiency was associated with slower hemoglobin decline early in treatment (week 4, P = 0.020) and rapid virologic response (RVR) at week 4 (P = 0.017) in patients coinfected with HIV and hepatitis C virus.