What is megestrol acetate used for?
Megestrol suspension is used to treat loss of appetite, malnutrition, and severe weight loss in patients with acquired immunodeficiency syndrome (AIDS). Megestrol should not be used to prevent loss of appetite and severe weight loss in patients who have not yet developed this condition.
What happens if you take megestrol?
Side Effects Trouble sleeping, fever, gas, decreased sexual ability/desire, weight gain, changes in appetite, or upset stomach may occur. Women may have changes in their menstrual periods, including unpredictable bleeding. If any of these effects last or get worse, tell your doctor or pharmacist promptly.
Can megestrol cause miscarriage?
Megestrol Pregnancy Warnings Risk Summary: Based on animal data, this drug can harm a developing fetus. There are no available human data to assess for any drug-associated risks of miscarriage, birth defects, or adverse maternal or fetal outcomes.
Can megace cause anemia?
In patients with cachexia: Diarrhea, flatulence, nausea, vomiting, hypertension, impotence, decreased libido, asthenia, rash, insomnia, anemia, fever, hyperglycemia, pain.
Who should not take megestrol?
You should not use megestrol if you are allergic to it, or if you are pregnant. Tell your doctor if you have ever had: diabetes; an adrenal gland disorder; or.
Why is Megace hazardous?
It has properties that interfere with the normal estrogen cycle. This interferes with the stimulation of cell growth in estrogen dependent tumor cells. There is also thought to be some direct effect on the lining of the uterine wall (endometrium). A side effect of megestrol has been weight gain.
Is megace used to stop bleeding?
Amongst the three treatment regimens, megestrol acetate was the fastest at suppressing uterine bleeding from a mean of 54 days to 3 days with the lowest bleeding score (4.9 ± 1.1). It was equally effective for treating both patients with and without endometrial hyperplasia who had ET of more than 11 mm.
What is the difference between megace and Megace ES?
Megace ES is a milky white, lemon-lime flavored oral suspension containing 125 mg of megestrol acetate per mL. Megace ES does not contain the same amount of megestrol acetate as Megace oral Megace ES is a milky white, lemon-lime flavored oral suspension containing 125 mg of megestrol acetate per mL.
Is megace harmful?
Megace must not be used during pregnancy. It may cause harm to a fetus. Women of childbearing age should use birth control while using this medication. This medication may pass into breast milk and could have undesirable effects on a nursing infant.
Who needs megace?
MEGACE Oral Suspension is indicated for the treatment of anorexia, cachexia, or an unexplained, significant weight loss in patients with a diagnosis of acquired immunodeficiency syndrome (AIDS). The recommended adult initial dosage of MEGACE Oral Suspension is 800 mg/day (20 mL/day).
How quickly does megace work?
Patients will typically improve their appetite within the first few weeks after starting the drug. Weight gain, often in the form of fat, may take longer. Resistance exercise traing coupled with the weight gain may lead to improved lean muscle mass. A typical treatment duration may be 12 weeks.
Is megace a steroid?
Chemistry. MGA, also known as 17α-acetoxy-6-dehydro-6-methylprogesterone or as 17α-acetoxy-6-methylpregna-4,6-diene-3,20-dione, is a synthetic pregnane steroid and a derivative of progesterone.
How should I take megestrol?
How to use megestrol oral Take this medication by mouth as directed by your doctor, usually once daily. Shake the bottle well before each dose. Carefully measure the dose using a special measuring…
Does megestrol cause weight gain?
Megestrol increases appetite and leads to weight gain. Among patients with AIDS, taking megestrol for 12 weeks can lead to weight gain of about 10 percent over the starting weight.
What is megestrol used for treating?
Megestrol is used to treat loss of appetite and wasting syndrome in people with acquired immunodeficiency syndrome (AIDS). Megestrol is not for use in preventing weight loss or wasting syndrome.
Does megestrol acetate cause hot flashes?
Preliminary data have suggested that megestrol acetate, a progestational agent, can decrease the frequency of hot flashes . A nonblinded study reported that megestrol acetate in daily doses of 20, 40, and 80 mg decreased menopausal hot flashes by 80, 89, and 98 percent, respectively 9.